When an individual is sexually aroused, the body releases nitric oxide, which stimulates the production of cyclic guanosine monophosphate (cGMP). This compound relaxes the muscles lining the blood vessels in the penis, allowing them to dilate and promote blood flow. However, in individuals with ED, the enzyme PDE5 breaks down cGMP prematurely, hindering the erection process.

Vidalista 40 inhibits the action of PDE5, preventing the premature degradation of cGMP and prolonging its effects. As a result, the blood vessels remain dilated for a longer duration, facilitating sustained erections and improved sexual performance.